Partial List of Publications from the CMSF

Development of piperazine-based hydroxamic acid inhibitors against falcilysin, an essential malarial protease.  Jeffrey P. Chance, Hannah Fejzic, Obiel Hernandez, Eva S. Istvan, Armann Andaya, Nikolay Maslov, Ruby Aispuro, Teodulo Crisanto, Huyen Nguyen, Brian Vidal, Whitney Serrano, Bradley Kuwahara, Corey Pugne Andanado, Daniel E. Goldberg, Jeremy P. Mallari. Bioorganic & Medicinal Chemistry Letters, Online 19 April 2018, ISSN 0960-894X,

The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding. (2017) Zhou, Coral Y. et al. Molecular Cell , Volume 69 , Issue 4 , 677 - 688.e9

Identification and verification of hybridoma-derived monoclonal antibody variable region sequences using recombinant DNA technology and mass spectrometry. (2017) Lmar Babrak, Jeffery A. McGarvey, Larry H. Stanker, Robert Hnasko. Molecular Immunology, Volume 90, Pages 287-294.!

Variation in MUTYH Expression in Arabian Horses with Cerebellar Abiotrophy. E.Y. Scott, K.D. Woolard, C.J. Finno, M.C.T. Penedo, J.D. Murray. , Brain Research, Available online 2 November 2017, ISSN 0006-8993,

Single-bead quantification of peptide loading distribution for One-Bead One-Compound library synthesis using confocal Raman spectroscopy. Yuchen Tang, Yann Thillier, Ruiwu Liu, Xiaocen Li, Kit S. Lam, and Tingjuan Gao Analytical Chemistry, May 2017 (just accepted manuscript). DOI:10.1021/acs.analchem.7b00516

Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase. Kin Sing Stephen Lee, Niel M. Henriksen, Connie J. Ng, Jun Yang, Weitao Jia, Christophe Morisseau, Armann Andaya, Michael K. Gilson, Bruce D. Hammock. Archives of Biochemistry and Biophysics, Volume 613, 2017,Pages 1-11.

Covalent Chemical Ligation Strategy for Mono- and Polyclonal Immunoglobulins at Their Nucleotide Binding Sites Diana Lac, Chun Feng, Gaurav Bhardwaj, Huong Le, Jimmy Tran, Li Xing, Gabriel Fung, Ruiwu Liu, Holland Cheng, and Kit S. Lam Bioconjugate Chemistry 2016 27 (1), 159-169.

Kin Sing Stephen Lee, Niel M. Henriksen, Connie J. Ng, Jun Yang, Weitao Jia, Christophe Morisseau, Armann Andaya, Michael K. Gilson, Bruce D. Hammock. Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase. Archives of Biochemistry and Biophysics, Available online 29 October 2016, ISSN 0003-9861. 

Michael A. Asensio, Norma M. Morella, Christopher M. Jakobson, Emily C. Hartman, Jeff E. Glasgow, Banumathi Sankaran, Peter H. Zwart, and Danielle Tullman-Ercek.  A Selection for Assembly Reveals That a Single Amino Acid Mutant of the Bacteriophage MS2 Coat Protein Forms a Smaller Virus-like Particle Nano Letters. Article ASAP DOI: 10.1021/acs.nanolett.6b02948 Publication Date (Web): August 23, 2016.

Wenwu Xiao, Tianhong Li, Fernanda C. Bononi, Diana Lac, Ivy A. Kekessie, Yanlei Liu, Eduardo Sanchez, Anisha Mazloom, Ai-hong Ma, Jia Lin, Jimmy Tran, Kevin Yang, Kit S. Lam and Ruiwu Liu. Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors. EJNMMI Research 2016 6:18, DOI: 10.1186/s13550-016-0165-z, 27 February 2016.

Mark Lemos, Yanmei Xiao, Marta Bjornson, Jin-zheng Wang, Derrick Hicks, Amancio de Souza, Chang-Quan Wang, Panyu Yang, Shisong Ma, Savithramma Dinesh-Kumar, and Katayoon DeheshThe plastidial retrograde signal methyl erythritol cyclopyrophosphate is a regulator of salicylic acid and jasmonic acid crosstalk.  J. Exp. Bot. first published online January 4, 2016 doi:10.1093/jxb/erv550.

Abolfazl Aghanouri, Charles F. Shoemaker, and Gang Sun (2015). Characterization of Conformational Structures of Plant Proteins in Solutions. Industrial & Engineering Chemistry Research, 54 (1), 188-197.

Kelly J. Phelps, Kiet Tran, Tristan Eifler, Anna I. Erickson, Andrew J. Fisher and Peter A. Beal (2015). Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2. Nucleic Acids Research, doi: 10.1093/nar/gku1345. First published online January 6th, 2015.

Kevin Y. Kima, Don-Hong Wanga, Mel Campbella, Steve B. Huertaa, Bogdan Shevchenkoa, Chie Izumiyaa and Yoshihiro Izumiyaa. (2015). PRMT4-Mediated Arginine Methylation Negatively Regulates Retinoblastoma Tumor Suppressor Protein and Promotes E2F-1 Dissociation. Mol. Cell. Biol. January 2015 vol. 35 no. 1 238-248.

Megan H. Touchette, Cynthia M. Holsclaw, Mary L. Previti, Viven C. Solomon, Julie A. Leary, Carolyn R. Bertozzie and Jessica C. Seeliger (2015). The rv1184c Locus Encodes Chp2, an Acyltransferase in Mycobacterium tuberculosis Polyacyltrehalose Lipid Biosynthesis. J. Bacteriol. January 2015 vol. 197 no. 1 201-210.

Jai Woong Seo, Lisa M. Mahakian, Sarah Tam, Shengping Qin, Elizabeth S. Ingham, Claude F. Meares, Katherine W. Ferrara, The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model, Nuclear Medicine and Biology, Volume 42, Issue 2, February 2015, Pages 155-163, ISSN 0969-8051,

Jai Woong Seo, Hyounggee Baek, Lisa M. Mahakian, Jiro Kusunose, Juliana Hamzah, Erkki Ruoslahti, and Katherine W. Ferrara (2014) 64Cu-Labeled LyP-1-Dendrimer for PET-CT Imaging of Atherosclerotic Plaque. Bioconjugate Chemistry, 25 (2), 231-239.

Kelly J Phelps, José M. Ibarra-Soza, Kiet Tran, Andrew J. Fisher, and Peter A. Beal (2014). Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA. ACS Chem. Biol. June 04 2014.

John L. Jacobsen, Patrick E. Berget, Michael C. Varela, Tony Vu, Neil E. Schore, Kathleen E. Martin, John A. Shelnutt, Luís M. Santos, Craig J. Medforth (2013).  Synthesis and Nanostructures of 5,10,15,20-Tetrakis(4-piperidyl)porphyrin.  Tetrahedron, Available online 25 September 2013,

Bezold, K. L., Shaffer, J. F., Khosa, J. K., Hoye, E. R., & Harris, S. P. (2013). A Gain-of-Function Mutation in the M-domain of Cardiac Myosin-binding Protein-C Increases Binding to Actin. Journal of Biological Chemistry, 288(30), 21496–21505.

Saludes JP, Gregar TQ, Monreal IA, Cook BM, Danan-Leon LM, Gervay-Hague J (2013). Solution phase conformation and proteolytic stability of amide-linked neuraminic acid analogues.Biopolymers, 99(10), 686-696;This made the cover. 

A.E. McClean, B.A. Duerkop, E.P. Greenberg, and D.A. Kluepfel (2012). AHL Signals Induce Rubrifacine Production in a bru I Mutant of Brenneria rubrifaciens. Phytopathology, 102(2), 195-203.

Benjamin M. Swarts, Cynthia M. Holsclaw, John C. Jewett, Marina Alber, Douglas M. Fox, M. Sloan Siegrist, Julie A. Leary, Rainer Kalscheuer, and Carolyn R. Bertozzi (2012). Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry. Journal of the American Chemical Society 2012 134 (39), 16123-16126.

W. Jia, A. Andaya, J. A. Leary (2012). Novel Mass Spectrometric Method for Phosphorylation Quantification Using Cerium Oxide Nanoparticles and Tandem Mass Tags. Analytical Chemistry, 84(5), 2466-2473.

M. R. Marcello, W. Jia, J. A. Leary, K. L. Moore, J. P. Evans (2011). Lack of Tyrosylprotein Sulfotransferase-2 Activity Results in Altered Sperm-Egg Interactions and Loss of ADAM3 and ADAM6 in Epididymal Sperm. Journal of Biological Chemistry, 286(15), 13060-13070.

Joan G. Go, Lieza M. Danan-Leon, Jessica A. Hoch, Aemro Kassa, Indresh Srivastava, David Davis, and Jacquelyn Gervay-Hague. (2011). Synthesis of a Trimeric gp120 Epitope Mimic Conjugated to a T-Helper Peptide to Improve Antigenicity.  J Am Chem Soc., 133(10): 3230–3233.

A. Andaya, W. Jia, M. Sokabe, C. S. Fraser, J. W. B. Hershey, J. A. Leary (2011). Phosphorylation of Human Eukaryotic Initiation Factor 2 gamma: Novel Site Identification and Targeted PKC Involvement. Journal of Proteome Research, 10(10), 4613-4623.

W. Jia, J. F. Shaffer, S. P. Harris, J. A. Leary (2010). Identification of Novel Protein Kinase A Phosphorylation Sites in the M-domain of Human and Murine Cardiac Myosin Binding Protein-C Using Mass Spectrometry Analysis. Journal of Proteome Research, 9(4), 1843-1853.

L. M. Danan, Z. Yu, P. J. Ludden, W. Jia, K. L. Moore, J. A. Leary (2010). Catalytic Mechanism of Golgi-Resident Human Tyrosylprotein Sulfotransferase-2: A Mass Spectrometry Approach. Journal of the American Society for Mass Spectrometry, 21(9), 1633-1642.

N.T. Pham, W.T. Jewell, D. Morin, and A.R. Buckpitt (2012). Analysis of naphthalene adduct binding sites in model proteins by tandem mass spectrometry. Chemico-Biological Interactions, 199(2), 120-8

N.T. Pham, W.T. Jewell, D. Morin, A.D. Jones, and A.R. Buckpitt (2012). Characterization of Model Peptide Adducts with Reactive Metabolites of Naphthalene by Mass Spectrometry. PloS One, 7(8), 42-53.

B.V. Marquez, H.E. Beck, T.A. Aweda, B. Phinney, C. Holsclaw, W. Jewell, D. Tran, J.J. Day, M.N. Peiris, C. Nwosu, and others (2012). Enhancing Peptide Ligand Binding to Vascular Endothelial Growth Factor by Covalent Bond Formation. Bioconjugate Chemistry, 23(5), 1080-1089.

W. Guo, R. Liu, Y. Ono, A.H. Ma, A. Martinez, E. Sanchez, Y. Wang, W. Huang, A. Mazloom, J. Li, and others (2012) Molecular Characteristics of CTA056, a Novel Itk Inhibitor Which Selectively Targets Malignant T Cells and Modulates Oncomirs. Molecular Pharmacology, Aug 2012 epub.

B.M. Swarts, C.M. Holsclaw, J.C. Jewett, M. Alber, D.M. Fox, M.S. Siegrist, J.A. Leary, R. Kalscheuer, and C.R. Bertozzi (2012). Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry. Journal of the American Chemical Society,Aug 2012, epub.

B. Tinsley (2012) The Ecological Roles Of Podostemum ceratophyllum and Cladophora in the Habitat and Dietary Preferences of the Riverine Caddisfly Hydropsyche Simulans, Thesis.

X.B. Liu, K.D. Murray, and E.G. Jones (2011). Low-threshold calcium channel subunit Cav3 is specifically localized in GABAergic neurons of rodent thalamus and cerebral cortex. The Journal of Comparative Neurology, 519(60), 1181-1195.

K. Hatzios, M.W. Schelle, G.L. Newton, K.M. Sogi, C.M. Holsclaw, R.C. Fahey, and C.R. Bertozzi (2011) The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth. Bioorganic & medicinal chemistry letters. 211(7), 4956-4959.

Schombs, F.E. Park, W. Du, S.S. Kulkarni, and J. Gervay-Hague (2010) One-Pot Syntheses of Immunostimulatory Glycolipids. The Journal of Organic Chemistry, 75(15), 4891-4898.

M.A. Witschi and J. Gervay-Hague (2010) Selective Acetylation of per-O-TMS-Protected Monosaccharides. Organic letters, 12194312.

P.C. Spiess, D. Morin, W.T. Jewell, and A.R. Buckpitt (2008). Measurement of protein sulfhydryls in response to cellular oxidative stress using gel electrophoresis and multiplexed fluorescent imaging analysis. Chemical Research in Toxicology, 21(5), 1074-1085.

Palandoken, K. By, M. Hegde, W.R. Harley, F.A. Gorin, and M.H. Nantz (2005). Amiloride peptide conjugates: prodrugs for sodium-proton exchange inhibition. Journal of Pharmacology and Experimental Therapeutics, 312 (3), 961-967.

R.T. Donham, A.D. Luna, S. Chang, D. Morin, W.T. Jewell, and R.S. Tjeerdema (2007). Characterization of cytosolic glutathione S-transferases in California Halibut (Paralichthys californicus). Ecotoxicology and Environmental Safety, 66(2), 133-138.

C.Y. Lin, M.A. Isbell, D. Morin, B.C. Boland, M.R. Salemi, W.T. Jewell, A.J. Weir, M.V. Fanucchi, G.L. Baker, C.G. Plopper, and others (2005). Characterization of a structurally intact in situ lung model and comparison of naphthalene protein adducts generated in this model vs lung microsomes. Chemical Research in Toxicology, 18(5), 802-813.

R.T. Donham, D. Morin, W.T. Jewell, MW Lame, HJ Segall, and R.S. Tjeerdema (2005). Characterization of cytosolic glutathione-S-transferases in juvenile Chinook salmon (Oncorhynchus tshawytscha). Aquatic Toxicology, 73(3), 221-229.

R.T. Donham, D. Morin, W.T. Jewell, S.A. Burns, A.E. Mitchell, MW Lame, HJ Segall, and R.S. Tjeerdema (2005) Characterization of glutathione-S-transferases in juvenile white sturgeon. Aquatic Toxicology, 71(3), 203-214.

R.M. Baldwin, W.T. Jewell, M.V. Fanucchi, C.G. Plopper, and A.R. Buckpitt2004Comparison of pulmonary/nasal CYP2F expression levels in rodents and rhesus macaque. Journal of Pharmacology and Experimental Therapeutics, 309(1), 127-136.